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A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis
During mitosis, translation of most mRNAs is strongly repressed; none of the several explanatory hypotheses suggested can fully explain the molecular basis of this phenomenon. Here we report that cyclin-dependent CDK11/p58—a serine/threonine kinase abundantly expressed during M phase—represses overa...
Autores principales: | An, Sihyeon, Kwon, Oh Sung, Yu, Jinbae, Jang, Sung Key |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599166/ https://www.ncbi.nlm.nih.gov/pubmed/32030451 http://dx.doi.org/10.1007/s00018-019-03436-3 |
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