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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality

In vivo transposon mutagenesis, coupled with deep sequencing, enables large-scale genome-wide mutant screens for genes essential in different growth conditions. We analyzed six large-scale studies performed on haploid strains of three yeast species (Saccharomyces cerevisiae, Schizosaccaromyces pombe...

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Detalles Bibliográficos
Autores principales: Levitan, Anton, Gale, Andrew N., Dallon, Emma K., Kozan, Darby W., Cunningham, Kyle W., Sharan, Roded, Berman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599172/
https://www.ncbi.nlm.nih.gov/pubmed/32681306
http://dx.doi.org/10.1007/s00294-020-01096-6