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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality
In vivo transposon mutagenesis, coupled with deep sequencing, enables large-scale genome-wide mutant screens for genes essential in different growth conditions. We analyzed six large-scale studies performed on haploid strains of three yeast species (Saccharomyces cerevisiae, Schizosaccaromyces pombe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599172/ https://www.ncbi.nlm.nih.gov/pubmed/32681306 http://dx.doi.org/10.1007/s00294-020-01096-6 |