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Carboplatin dose capping affects pCR rate in HER2-positive breast cancer patients treated with neoadjuvant Docetaxel, Carboplatin, Trastuzumab, Pertuzumab (TCHP)

PURPOSE: Estimated glomerular filtration rate (eGFR) is commonly used to calculate carboplatin doses and capping the eGFR may be used to reduce the risk of excessive dosing and toxicity. We sought to retrospectively examine the impact of our carboplatin guidelines on pathological complete response r...

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Detalles Bibliográficos
Autores principales: Howell, Sacha J., Coe, Faye, Wang, Xin, Horsley, Laura, Ekholm, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599187/
https://www.ncbi.nlm.nih.gov/pubmed/32860550
http://dx.doi.org/10.1007/s10549-020-05868-z