Fenofibrate prevents iron induced activation of canonical Wnt/β-catenin and oxidative stress signaling in the retina

Accumulating evidence strongly implicates iron in the pathogenesis of aging and disease. Iron levels have been found to increase with age in both the human and mouse retinas. We and others have shown that retinal diseases such as age-related macular degeneration and diabetic retinopathy are associat...

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Detalles Bibliográficos
Autores principales: Mandala, Ashok, Armstrong, Austin, Girresch, Becky, Zhu, Jiyao, Chilakala, Aruna, Chavalmane, Sanmathi, Chaudhary, Kapil, Biswas, Pratim, Ogilvie, Judith, Gnana-Prakasam, Jaya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599211/
https://www.ncbi.nlm.nih.gov/pubmed/33145027
http://dx.doi.org/10.1038/s41514-020-00050-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599211/
https://www.ncbi.nlm.nih.gov/pubmed/33145027
http://dx.doi.org/10.1038/s41514-020-00050-7

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