Cargando…

Fenofibrate prevents iron induced activation of canonical Wnt/β-catenin and oxidative stress signaling in the retina

Accumulating evidence strongly implicates iron in the pathogenesis of aging and disease. Iron levels have been found to increase with age in both the human and mouse retinas. We and others have shown that retinal diseases such as age-related macular degeneration and diabetic retinopathy are associat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mandala, Ashok, Armstrong, Austin, Girresch, Becky, Zhu, Jiyao, Chilakala, Aruna, Chavalmane, Sanmathi, Chaudhary, Kapil, Biswas, Pratim, Ogilvie, Judith, Gnana-Prakasam, Jaya P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599211/ https://www.ncbi.nlm.nih.gov/pubmed/33145027 http://dx.doi.org/10.1038/s41514-020-00050-7

Ejemplares similares

Canonical Wnt Signaling in the Pathology of Iron Overload-Induced Oxidative Stress and Age-Related Diseases
por: Armstrong, Austin, et al.
Publicado: (2022)

Quantitative Understanding of Nanoparticle Uptake in Watermelon Plants
por: Raliya, Ramesh, et al.
Publicado: (2016)

Effects of Fenofibrate on Adiponectin Expression in Retinas of Streptozotocin-Induced Diabetic Rats
por: Hsu, Ying-Jung, et al.
Publicado: (2014)

Role of Iron in Aging Related Diseases
por: Chen, William J., et al.
Publicado: (2022)

Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression
por: Chaudhary, Kapil, et al.
Publicado: (2018)

A Review of Currently Available Fenofibrate and Fenofibric Acid Formulations
por: Ling, Hua, et al.
Publicado: (2013)

Effects of Modified Low-Density Lipoproteins and Fenofibrate on an Outer Blood-Retina Barrier Model: Implications for Diabetic Retinopathy
por: Fu, Dongxu, et al.
Publicado: (2020)

Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
por: Kolesnikov, Alexander V., et al.
Publicado: (2022)

A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy
por: Strain, Joe D, et al.
Publicado: (2010)

Cannabidiol and the Canonical WNT/β-Catenin Pathway in Glaucoma
por: Vallée, Alexandre, et al.
Publicado: (2021)

Fibrane the reduced derivative of fenofibrate
por: Kotheimer, Amanda E., et al.
Publicado: (2019)

Retinal expression of the serine protease matriptase-2 (Tmprss6) and its role in retinal iron homeostasis
por: Gnana-Prakasam, Jaya P., et al.
Publicado: (2014)

Maillard Reaction Crosslinked Alginate-Albumin Scaffolds for Enhanced Fenofibrate Delivery to the Retina: A Promising Strategy to Treat RPE-Related Dysfunction
por: Abedin Zadeh, Maria, et al.
Publicado: (2023)

Comparison of efficacy and safety of choline fenofibrate (fenofibric acid) to micronized fenofibrate in patients of mixed dyslipidemia: A randomized, open-label, multicenter clinical trial in Indian population
por: Patel, Piyush, et al.
Publicado: (2016)

Targeting the canonical Wnt/β-catenin pathway in hematological malignancies
por: Ashihara, Eishi, et al.
Publicado: (2015)

New Advances in Canonical Wnt/β-Catenin Signaling in Cancer
por: Wen, Xiaolan, et al.
Publicado: (2020)

Multiple Targets of the Canonical WNT/β-Catenin Signaling in Cancers
por: Lecarpentier, Yves, et al.
Publicado: (2019)

Identification of Wnt/β-catenin modulated genes in the developing retina
por: Ha, Andrew, et al.
Publicado: (2012)

Rosiglitazone and Fenofibrate Additive Effects on Lipids
por: Slim, Ahmad, et al.
Publicado: (2011)

Detecting responses to treatment with fenofibrate in pedigrees
por: Cherlin, Svetlana, et al.
Publicado: (2018)

Effect of Fenofibrate Medication on Renal Function
por: Kim, Sungjong, et al.
Publicado: (2017)

Fenofibrate-induced renal dysfunction, yes or no?
por: Emami, Fatemeh, et al.
Publicado: (2020)

The role of fenofibrate in the treatment of COVID-19
por: Yasmin, Farah, et al.
Publicado: (2021)

Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation
por: Hägglund, Anna-Carin, et al.
Publicado: (2013)

Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling
por: Janda, Claudia Y., et al.
Publicado: (2017)

The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
por: You, Hongjuan, et al.
Publicado: (2022)

Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]
Publicado: (2005)

β-Catenin Inactivation Is a Pre-Requisite for Chick Retina Regeneration
por: Zhu, Jie, et al.
Publicado: (2014)

Fenofibrate: direct attenuating effects on tumor growth
por: Kapoor, Shailendra
Publicado: (2013)

Uridine Prevents Fenofibrate-Induced Fatty Liver
por: Le, Thuc T., et al.
Publicado: (2014)

Pleiotropic effects of fenofibrate therapy on rats with hypertriglycemia
por: Sun, Bing, et al.
Publicado: (2015)

Anticancer Properties of Fenofibrate: A Repurposing Use
por: Lian, Xin, et al.
Publicado: (2018)

Identifying fenofibrate responsive CpG sites
por: Cantor, Rita, et al.
Publicado: (2018)

Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential()()
por: Stalinska, J., et al.
Publicado: (2019)

Anti-inflammatory role of fenofibrate in treating diseases
por: Jin, Lv, et al.
Publicado: (2023)

Expression of canonical WNT/β-CATENIN signaling components in the developing human lung
por: Zhang, Mingfeng, et al.
Publicado: (2012)

Human Cytomegalovirus Infection Dysregulates the Canonical Wnt/β-catenin Signaling Pathway
por: Angelova, Magdalena, et al.
Publicado: (2012)

Canonical WNT/β-Catenin Signaling Plays a Subordinate Role in Rhabdomyosarcomas
por: Ragab, Nada, et al.
Publicado: (2018)

Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro
por: Zhou, Zhou, et al.
Publicado: (2012)

Fenofibrate in Primary Biliary Cirrhosis: A Pilot Study
por: Liberopoulos, E.N, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_bfjn3m7s69505o3tantmb50ha6