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Dynamic networks observed in the nucleosome core particles couple the histone globular domains with DNA

The dynamics of eukaryotic nucleosomes are essential in gene activity and well regulated by various factors. Here, we elucidated the internal dynamics at multiple timescales for the human histones hH3 and hH4 in the Widom 601 nucleosome core particles (NCP), suggesting that four dynamic networks are...

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Detalles Bibliográficos
Autores principales: Shi, Xiangyan, Prasanna, Chinmayi, Soman, Aghil, Pervushin, Konstantin, Nordenskiöld, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599221/
https://www.ncbi.nlm.nih.gov/pubmed/33128005
http://dx.doi.org/10.1038/s42003-020-01369-3