Cargando…

Dynamic networks observed in the nucleosome core particles couple the histone globular domains with DNA

The dynamics of eukaryotic nucleosomes are essential in gene activity and well regulated by various factors. Here, we elucidated the internal dynamics at multiple timescales for the human histones hH3 and hH4 in the Widom 601 nucleosome core particles (NCP), suggesting that four dynamic networks are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Xiangyan, Prasanna, Chinmayi, Soman, Aghil, Pervushin, Konstantin, Nordenskiöld, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599221/ https://www.ncbi.nlm.nih.gov/pubmed/33128005 http://dx.doi.org/10.1038/s42003-020-01369-3

Ejemplares similares

Structural and dynamical investigation of histone H2B in well-hydrated nucleosome core particles by solid-state NMR
por: Shi, Xiangyan, et al.
Publicado: (2023)

A systematic analysis of nucleosome core particle and nucleosome-nucleosome stacking structure
por: Korolev, Nikolay, et al.
Publicado: (2018)

An Advanced Coarse-Grained Nucleosome Core Particle Model for Computer Simulations of Nucleosome-Nucleosome Interactions under Varying Ionic Conditions
por: Fan, Yanping, et al.
Publicado: (2013)

The human telomeric nucleosome displays distinct structural and dynamic properties
por: Soman, Aghil, et al.
Publicado: (2020)

Regulation of chaperone binding and nucleosome dynamics by key residues within the globular domain of histone H3
por: Hainer, Sarah J., et al.
Publicado: (2016)

DNA Damage by Histone Radicals in Nucleosome Core Particles
por: Zhou, Chuanzheng, et al.
Publicado: (2014)

Reconstituted TAD-size chromatin fibers feature heterogeneous nucleosome clusters
por: Korolev, Nikolay, et al.
Publicado: (2022)

Correlating histone acetylation with nucleosome core particle dynamics and function
por: Kim, Tae Hun, et al.
Publicado: (2023)

Novel nucleosomal particles containing core histones and linker DNA but no histone H1
por: Cole, Hope A., et al.
Publicado: (2016)

3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM
por: Chua, Eugene Y.D., et al.
Publicado: (2016)

Structural Paradigms in the Recognition of the Nucleosome Core Particle by Histone Lysine Methyltransferases
por: Janna, Ashley, et al.
Publicado: (2020)

Chromatin Liquid–Liquid Phase Separation (LLPS) Is Regulated by Ionic Conditions and Fiber Length
por: Chen, Qinming, et al.
Publicado: (2022)

Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones
por: Sato, Shoko, et al.
Publicado: (2021)

Linker histone defines structure and self-association behaviour of the 177 bp human chromatosome
por: Wang, Sai, et al.
Publicado: (2021)

Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes
por: Shoaib, Muhammad, et al.
Publicado: (2021)

A Bottom-Up Coarse-Grained Model for Nucleosome–Nucleosome Interactions with Explicit Ions
por: Sun, Tiedong, et al.
Publicado: (2022)

Trajectories of microsecond molecular dynamics simulations of nucleosomes and nucleosome core particles
por: Shaytan, Alexey K., et al.
Publicado: (2016)

Histone H3 globular domain acetylation identifies a new class of enhancers
por: Pradeepa, Madapura M, et al.
Publicado: (2016)

Elucidation of binding preferences of YEATS domains to site-specific acetylated nucleosome core particles
por: Kikuchi, Masaki, et al.
Publicado: (2022)

A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones
Publicado: (1987)

Constraints on the coupling with photons of heavy axion-like-particles from Globular Clusters
por: Carenza, Pierluca, et al.
Publicado: (2020)

Mass Spectrometric Characterization of Histone H3 Isolated from in-Vitro Reconstituted and Acetylated Nucleosome Core Particle
por: Saikusa, Kazumi, et al.
Publicado: (2020)

Nucleosomal arrays self‐assemble into supramolecular globular structures lacking 30‐nm fibers
por: Maeshima, Kazuhiro, et al.
Publicado: (2016)

Histone modifications regulate DNA replication coupled nucleosome assembly
por: Han, Junhong, et al.
Publicado: (2013)

Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle
por: Tsunaka, Yasuo, et al.
Publicado: (2005)

Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome
por: Furukawa, Ayako, et al.
Publicado: (2022)

Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome
por: Furukawa, Ayako, et al.
Publicado: (2022)

Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
por: Wakamori, Masatoshi, et al.
Publicado: (2015)

Scooby-domain: prediction of globular domains in protein sequence
por: George, Richard A., et al.
Publicado: (2005)

Cryo-EM of nucleosome core particle interactions in trans
por: Bilokapic, Silvija, et al.
Publicado: (2018)

The Role of Histone Modification in DNA Replication-Coupled Nucleosome Assembly and Cancer
por: Zhang, Yaguang, et al.
Publicado: (2023)

Structure, dynamics, and stability of the globular domain of human linker histone H1.0 and the role of positive charges
por: Martinsen, Jacob H., et al.
Publicado: (2022)

Unencumbered Pol β lyase activity in nucleosome core particles
por: Rodriguez, Yesenia, et al.
Publicado: (2017)

The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats
por: Bowman, Andrew, et al.
Publicado: (2016)

Chromatin compaction under mixed salt conditions: Opposite effects of sodium and potassium ions on nucleosome array folding
por: Allahverdi, Abdollah, et al.
Publicado: (2015)

Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer
por: Clapier, Cedric R, et al.
Publicado: (2008)

Synthetic hyperacetylation of nucleosomal histones
por: Kajino, Hidetoshi, et al.
Publicado: (2020)

Nucleosome proteostasis and histone turnover
por: Arrieta, Adrian, et al.
Publicado: (2022)

Inter-nucleosomal communication between histone modifications for nucleosome phasing
por: Chen, Weizhong, et al.
Publicado: (2018)

Histones participate in base excision repair of 8-oxodGuo by transiently cross-linking with active repair intermediates in nucleosome core particles
por: Ren, Mengtian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_eo2kjnt7jthjhg0mpv3hir8td3