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Aglycosylated antibody-producing mice for aglycosylated antibody-lectin coupled immunoassay for the quantification of tumor markers (ALIQUAT)

Targeting aberrant glycoforms has been validated for in vitro cancer diagnostic development, and several assays are currently in routine clinical use. Because N-glycans in Fc region of antibodies show cross-reactivity with various lectins, high-quality aglycosylated antibodies are exceptionally impo...

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Detalles Bibliográficos
Autores principales: Lee, Nan-Ee, Kim, Sun Hee, Yu, Dae-Yeul, Woo, Eui-Jeon, Kim, Myung-Il, Seong, Gi-Sang, Lee, Sun Min, Ko, Jeong-Heon, Kim, Yong-Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599229/
https://www.ncbi.nlm.nih.gov/pubmed/33128033
http://dx.doi.org/10.1038/s42003-020-01363-9