HO-1/PINK1 Regulated Mitochondrial Fusion/Fission to Inhibit Pyroptosis and Attenuate Septic Acute Kidney Injury

BACKGROUND: Endotoxin-associated acute kidney injury (AKI), a disease characterized by marked oxidative stress and inflammation disease, is a major cause of mortality in critically ill patients. Mitochondrial fission and pyroptosis often occur in AKI. However, the underlying biological pathways invo...

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Detalles Bibliográficos
Autores principales: Li, Hai-Bo, Zhang, Xi-Zhe, Sun, Yi, Zhou, Qi, Song, Jian-Nan, Hu, Zhan-Fei, Li, Yun, Wu, Jian-Nan, Guo, Ying, Zhang, Yuan, Shi, Jia, Yu, Jian-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599399/
https://www.ncbi.nlm.nih.gov/pubmed/33145342
http://dx.doi.org/10.1155/2020/2148706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599399/
https://www.ncbi.nlm.nih.gov/pubmed/33145342
http://dx.doi.org/10.1155/2020/2148706

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