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HO-1/PINK1 Regulated Mitochondrial Fusion/Fission to Inhibit Pyroptosis and Attenuate Septic Acute Kidney Injury
BACKGROUND: Endotoxin-associated acute kidney injury (AKI), a disease characterized by marked oxidative stress and inflammation disease, is a major cause of mortality in critically ill patients. Mitochondrial fission and pyroptosis often occur in AKI. However, the underlying biological pathways invo...
Autores principales: | Li, Hai-Bo, Zhang, Xi-Zhe, Sun, Yi, Zhou, Qi, Song, Jian-Nan, Hu, Zhan-Fei, Li, Yun, Wu, Jian-Nan, Guo, Ying, Zhang, Yuan, Shi, Jia, Yu, Jian-Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599399/ https://www.ncbi.nlm.nih.gov/pubmed/33145342 http://dx.doi.org/10.1155/2020/2148706 |
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