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Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1β and Interleukin-18 from Human Monocytes

Inflammasomes cleave and activate interleukin- (IL-) 1β and IL-18 which have both shared and unique biological functions. IL-1β is an important mediator of the acute phase response to infections and tissue damage, whereas IL-18 takes part in activation and tailoring of the adaptive immune response....

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Detalles Bibliográficos
Autores principales: Midtbö, Kristine, Eklund, Daniel, Särndahl, Eva, Persson, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599400/
https://www.ncbi.nlm.nih.gov/pubmed/33144845
http://dx.doi.org/10.1155/2020/4651090