Data on the generation of two Nr2e3 mouse models by CRISPR / Cas9D10A nickase

NR2E3 encodes an orphan nuclear receptor that plays a dual function as both transcriptional activator and repressor in photoreceptors, being necessary for cone fate inhibition as well as rod differentiation and homeostasis. Mutations in this gene cause retinitis pigmentosa (RP), enhanced S cone synd...

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Detalles Bibliográficos
Autores principales: Aísa-Marín, Izarbe, López-Iniesta, M. José, Marfany, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599427/
https://www.ncbi.nlm.nih.gov/pubmed/33163596
http://dx.doi.org/10.1016/j.dib.2020.106447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599427/
https://www.ncbi.nlm.nih.gov/pubmed/33163596
http://dx.doi.org/10.1016/j.dib.2020.106447

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