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Data on the generation of two Nr2e3 mouse models by CRISPR / Cas9D10A nickase
NR2E3 encodes an orphan nuclear receptor that plays a dual function as both transcriptional activator and repressor in photoreceptors, being necessary for cone fate inhibition as well as rod differentiation and homeostasis. Mutations in this gene cause retinitis pigmentosa (RP), enhanced S cone synd...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599427/ https://www.ncbi.nlm.nih.gov/pubmed/33163596 http://dx.doi.org/10.1016/j.dib.2020.106447 |