Indoxylsulfate, a Metabolite of the Microbiome, Has Cytostatic Effects in Breast Cancer via Activation of AHR and PXR Receptors and Induction of Oxidative Stress

SIMPLE SUMMARY: The aim of our study was to identify metabolites of bacterial origin that play role in the pathogenesis of breast cancer. We identified indoxylsulfate, a metabolite of the amino acid tryptophan, as a metabolite with cytostatic properties on breast cancer cells. Cytostatic properties...

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Detalles Bibliográficos
Autores principales: Sári, Zsanett, Mikó, Edit, Kovács, Tünde, Boratkó, Anita, Ujlaki, Gyula, Jankó, Laura, Kiss, Borbála, Uray, Karen, Bai, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599465/
https://www.ncbi.nlm.nih.gov/pubmed/33050543
http://dx.doi.org/10.3390/cancers12102915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599465/
https://www.ncbi.nlm.nih.gov/pubmed/33050543
http://dx.doi.org/10.3390/cancers12102915

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