Cargando…

Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways

SIMPLE SUMMARY: Investigation into effective targets of drug resistance is important for identifying novel strategies in cancer therapy. The study aimed to determine the functional role of paclitaxel (PTX) resistance on MCF-7 cell survival related to PI3K/Akt and MAPK pathways. Therefore, we generat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ozfiliz Kilbas, Pelin, Sonmez, Ozlem, Uysal-Onganer, Pinar, Coker Gurkan, Ajda, Obakan Yerlikaya, Pinar, Arisan, Elif Damla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599514/
https://www.ncbi.nlm.nih.gov/pubmed/33019717
http://dx.doi.org/10.3390/biology9100320