Absence of BCL-2 Expression Identifies a Subgroup of AML with Distinct Phenotypic, Molecular, and Clinical Characteristics

Acute myeloid leukemia (AML) is a hematologic malignancy characterized by the rapid and uncontrolled clonal growth of myeloid lineage cells in the bone marrow. The advent of oral, selective inhibitors of the B-cell leukemia/lymphoma-2 (BCL-2) apoptosis pathway, such as venetoclax, will likely induce...

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Detalles Bibliográficos
Autores principales: haes, Inke De, Dendooven, Amélie, Mercier, Marie Le, Puylaert, Pauline, Vermeulen, Katrien, Kockx, Mark, Deiteren, Kathleen, Maes, Marie-Berthe, Berneman, Zwi, Anguille, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599534/
https://www.ncbi.nlm.nih.gov/pubmed/32992732
http://dx.doi.org/10.3390/jcm9103090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599534/
https://www.ncbi.nlm.nih.gov/pubmed/32992732
http://dx.doi.org/10.3390/jcm9103090

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