DUX Hunting—Clinical Features and Diagnostic Challenges Associated with DUX4-Rearranged Leukaemia

SIMPLE SUMMARY: DUX4-rearrangement (DUX4r) is a recently discovered recurrent genomic lesion reported in 4–7% of childhood B cell acute lymphoblastic leukaemia (B-ALL) cases. This subtype has favourable outcomes, especially in children and adolescents treated with intensive chemotherapy. The fusion...

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Detalles Bibliográficos
Autores principales: Rehn, Jacqueline A., O’Connor, Matthew J., White, Deborah L., Yeung, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599557/
https://www.ncbi.nlm.nih.gov/pubmed/33007870
http://dx.doi.org/10.3390/cancers12102815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599557/
https://www.ncbi.nlm.nih.gov/pubmed/33007870
http://dx.doi.org/10.3390/cancers12102815

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