Cargando…
DUX Hunting—Clinical Features and Diagnostic Challenges Associated with DUX4-Rearranged Leukaemia
SIMPLE SUMMARY: DUX4-rearrangement (DUX4r) is a recently discovered recurrent genomic lesion reported in 4–7% of childhood B cell acute lymphoblastic leukaemia (B-ALL) cases. This subtype has favourable outcomes, especially in children and adolescents treated with intensive chemotherapy. The fusion...
Autores principales: | Rehn, Jacqueline A., O’Connor, Matthew J., White, Deborah L., Yeung, David T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599557/ https://www.ncbi.nlm.nih.gov/pubmed/33007870 http://dx.doi.org/10.3390/cancers12102815 |
Ejemplares similares
-
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4
por: Eidahl, Jocelyn O., et al.
Publicado: (2016) -
Telomeres cooperate in zygotic genome activation by affecting DUX4/Dux transcription
por: Zhang, Xiaorui, et al.
Publicado: (2023) -
Analysis of DUX4 Expression in Bone Marrow and Re-Discussion of DUX4 Function in the Health and Disease
por: Hangul, Ceren, et al.
Publicado: (2022) -
Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation
por: Ansseau, Eugénie, et al.
Publicado: (2016) -
DUX4(HD2)-DNA(ERG) structure reveals new insight into DUX4-Responsive-Element
por: Dong, Xue, et al.
Publicado: (2018)