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Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas

Glutamine is a non-essential amino acid that plays a key role in the metabolism of proliferating cells including neoplastic cells. In the central nervous system (CNS), glutamine metabolism is particularly relevant, because the glutamine-glutamate cycle is a way of controlling the production of gluta...

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Detalles Bibliográficos
Autores principales: Martins, Filipa, Gonçalves, Luís G., Pojo, Marta, Serpa, Jacinta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599606/
https://www.ncbi.nlm.nih.gov/pubmed/32993063
http://dx.doi.org/10.3390/biom10101370