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Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas
Glutamine is a non-essential amino acid that plays a key role in the metabolism of proliferating cells including neoplastic cells. In the central nervous system (CNS), glutamine metabolism is particularly relevant, because the glutamine-glutamate cycle is a way of controlling the production of gluta...
Autores principales: | Martins, Filipa, Gonçalves, Luís G., Pojo, Marta, Serpa, Jacinta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599606/ https://www.ncbi.nlm.nih.gov/pubmed/32993063 http://dx.doi.org/10.3390/biom10101370 |
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