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Mitochondrial ROS1 Increases Mitochondrial Fission and Respiration in Oral Squamous Cancer Carcinoma

SIMPLE SUMMARY: The clinical efficacy of anti-epidermal growth factor receptor (EGFR) antibody cetuximab for oral squamous cell carcinomas (OSCCs) is low. We previously reported that an increased oncogenic ROS proto-oncogene 1 (ROS1) is responsible for the invasiveness and metastasis of OSCC. This s...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Jung, Chen, Kuan-Wei, Chen, Linyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599653/
https://www.ncbi.nlm.nih.gov/pubmed/33019722
http://dx.doi.org/10.3390/cancers12102845