CD99–PTPN12 Axis Suppresses Actin Cytoskeleton-Mediated Dimerization of Epidermal Growth Factor Receptor

SIMPLE SUMMARY: The epidermal growth factor receptor (EGFR) is activated through growth factor-dependent dimerization accompanied by functional reorganization of the actin cytoskeleton. Lee et al. demonstrate that CD99 activation by agonist ligands inhibits epidermal growth factor (EGF)-induced EGFR...

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Detalles Bibliográficos
Autores principales: Lee, Kyoung-Jin, Kim, Yuri, Kim, Min Seo, Ju, Hyun-Mi, Choi, Boyoung, Lee, Hansoo, Jeoung, Dooil, Moon, Ki-Won, Kang, Dongmin, Choi, Jiwon, Yook, Jong In, Hahn, Jang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599698/
https://www.ncbi.nlm.nih.gov/pubmed/33050232
http://dx.doi.org/10.3390/cancers12102895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599698/
https://www.ncbi.nlm.nih.gov/pubmed/33050232
http://dx.doi.org/10.3390/cancers12102895

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