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Deletion of Budding Yeast MAD2 Suppresses Clone-to-Clone Differences in Artificial Linear Chromosome Copy Numbers and Gives Rise to Higher Retention Rates

Our goal was to investigate the changes in artificial short-linear chromosome average copy numbers per cell arising from partial or full loss of Mitotic Arrest-Deficient 2 (MAD2) spindle checkpoint function in budding yeast Saccharomyces cerevisiae. Average artificial linear chromosome copy numbers...

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Detalles Bibliográficos
Autores principales: Schuyler, Scott C., Wang, Lin-Ing, Ding, Yi-Shan, Lee, Yi-Chieh, Chen, Hsin-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599710/
https://www.ncbi.nlm.nih.gov/pubmed/33003307
http://dx.doi.org/10.3390/microorganisms8101495