Cargando…

Long-Term Helicobacter pylori Infection Switches Gastric Epithelium Reprogramming towards Cancer Stem Cell-Related Differentiation Program in Hp-Activated Gastric Fibroblast-TGFβ Dependent Manner

Helicobacter pylori (Hp)-induced inflammatory reaction leads to a persistent disturbance of gastric mucosa and chronic gastritis evidenced by deregulation of tissue self-renewal and local fibrosis with the crucial role of epithelial–mesenchymal transition (EMT) in this process. As we reported before...

Descripción completa

Detalles Bibliográficos
Autores principales: Krzysiek-Maczka, Gracjana, Targosz, Aneta, Szczyrk, Urszula, Wrobel, Tomasz, Strzalka, Malgorzata, Brzozowski, Tomasz, Czyz, Jaroslaw, Ptak-Belowska, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599721/
https://www.ncbi.nlm.nih.gov/pubmed/33023180
http://dx.doi.org/10.3390/microorganisms8101519