Effect of Antibiotic Susceptibility and CYP3A4/5 and CYP2C19 Genotype on the Outcome of Vonoprazan-Containing Helicobacter pylori Eradication Therapy

Background: Helicobacter pylori eradication containing the potassium-competitive acid blocker, vonoprazan, achieves a higher eradication rate than therapy with proton pump inhibitors (PPIs). Because vonoprazan is mainly metabolized by CYP3A4/5, CYP genotype may affect the eradication rate. We invest...

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Detalles Bibliográficos
Autores principales: Sugimoto, Mitsushige, Hira, Daiki, Murata, Masaki, Kawai, Takashi, Terada, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599771/
https://www.ncbi.nlm.nih.gov/pubmed/32993151
http://dx.doi.org/10.3390/antibiotics9100645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599771/
https://www.ncbi.nlm.nih.gov/pubmed/32993151
http://dx.doi.org/10.3390/antibiotics9100645

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