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Multivariate Analytical Approaches to Identify Key Molecular Properties of Vehicles, Permeants and Membranes That Affect Permeation through Membranes

There has been considerable recent interest in employing computer models to investigate the relationship between the structure of a molecule and its dermal penetration. Molecular permeation across the epidermis has previously been demonstrated to be determined by a number of physicochemical properti...

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Detalles Bibliográficos
Autores principales: Najib, Omaima N., Kirton, Stewart B., Martin, Gary P., Botha, Michelle J., Sallam, Al-Sayed, Murnane, Darragh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599860/
https://www.ncbi.nlm.nih.gov/pubmed/33050611
http://dx.doi.org/10.3390/pharmaceutics12100958