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Cocoa (Theobroma cacao L.) Seed Proteins’ Anti-Obesity Potential through Lipase Inhibition Using In Silico, In Vitro and In Vivo Models

The aim of this study was to determine the pancreatic lipase (PL) inhibitory effect of cocoa protein (CP) hydrolysates (CPH) using in silico and in vitro approaches, and an in vivo high-fat diet (HF) obese rat model. The results showed better theoretical affinity on PL for cocoa peptides EEQR, GGER,...

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Detalles Bibliográficos
Autores principales: Coronado-Cáceres, Luis Jorge, Rabadán-Chávez, Griselda, Mojica, Luis, Hernández-Ledesma, Blanca, Quevedo-Corona, Lucía, Lugo Cervantes, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599879/
https://www.ncbi.nlm.nih.gov/pubmed/32992701
http://dx.doi.org/10.3390/foods9101359