A Marine Alkaloid, Ascomylactam A, Suppresses Lung Tumorigenesis via Inducing Cell Cycle G1/S Arrest through ROS/Akt/Rb Pathway

Ascomylactam A was reported for the first time as a new 13-membered-ring macrocyclic alkaloid in 2019 from the mangrove endophytic fungus Didymella sp. CYSK-4 from the South China Sea. The aim of our study was to delineate the effects of ascomylactam A (AsA) on lung cancer cells and explore the anti...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Huang, Yun, Huang, Cui-hong, Yu, Jian-chen, Zheng, Ying-chun, Chen, Yan, She, Zhi-gang, Yuan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599880/
https://www.ncbi.nlm.nih.gov/pubmed/32992455
http://dx.doi.org/10.3390/md18100494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599880/
https://www.ncbi.nlm.nih.gov/pubmed/32992455
http://dx.doi.org/10.3390/md18100494

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