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Dissecting G(q/11)-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1

Diverse extracellular signals induce plasma membrane translocation of sphingosine kinase-1 (SphK1), thereby enabling inside-out signaling of sphingosine-1-phosphate. We have shown before that G(q)-coupled receptors and constitutively active Gα(q/11) specifically induced a rapid and long-lasting SphK...

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Detalles Bibliográficos
Autores principales: Blankenbach, Kira Vanessa, Claas, Ralf Frederik, Aster, Natalie Judith, Spohner, Anna Katharina, Trautmann, Sandra, Ferreirós, Nerea, Black, Justin L., Tesmer, John J. G., Offermanns, Stefan, Wieland, Thomas, Meyer zu Heringdorf, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599897/
https://www.ncbi.nlm.nih.gov/pubmed/33003441
http://dx.doi.org/10.3390/cells9102201