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PD-1 Expression by Lymph Node and Intratumoral Regulatory T Cells Is Associated with Lymph Node Metastasis in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer is a devastating disease and among the most immune-resistant tumor types. Single-agent immunotherapy has not demonstrated clinical benefits in pancreatic cancer patients, and combinational therapies targeting multiple mechanisms of immunosuppression are likely neede...

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Detalles Bibliográficos
Autores principales: Seifert, Adrian M., Eymer, Annabel, Heiduk, Max, Wehner, Rebekka, Tunger, Antje, von Renesse, Janusz, Decker, Rahel, Aust, Daniela E., Welsch, Thilo, Reissfelder, Christoph, Weitz, Jürgen, Schmitz, Marc, Seifert, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599971/
https://www.ncbi.nlm.nih.gov/pubmed/32987956
http://dx.doi.org/10.3390/cancers12102756