Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer’s Disease

High-fat diet (HFD) has been shown to accelerate Alzheimer’s disease (AD) pathology, but the exact molecular and cellular mechanisms remain incompletely understood. Moreover, it is unknown whether AD mice are more susceptible to HFD-induced metabolic dysfunctions. To address these questions, we used...

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Detalles Bibliográficos
Autores principales: Reilly, Austin M., Tsai, Andy P., Lin, Peter B., Ericsson, Aaron C., Oblak, Adrian L., Ren, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600118/
https://www.ncbi.nlm.nih.gov/pubmed/33003412
http://dx.doi.org/10.3390/nu12102977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600118/
https://www.ncbi.nlm.nih.gov/pubmed/33003412
http://dx.doi.org/10.3390/nu12102977

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