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Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits

Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in the developed world, yet no pharmacological therapy exists. Here, we hypothesize that the integration of multiple omic data represents an approach towards unveiling novel molecular networks in CAVD. Databases were s...

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Detalles Bibliográficos
Autores principales: Heuschkel, Marina A., Skenteris, Nikolaos T., Hutcheson, Joshua D., van der Valk, Dewy D., Bremer, Juliane, Goody, Philip, Hjortnaes, Jesper, Jansen, Felix, Bouten, Carlijn V.C., van den Bogaerdt, Antoon, Matic, Ljubica, Marx, Nikolaus, Goettsch, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600313/
https://www.ncbi.nlm.nih.gov/pubmed/32987857
http://dx.doi.org/10.3390/cells9102164