Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro

Magnolol (MG) is the main active compound of Magnolia officinalis and exerts a wide range of biological activities. In this study, we investigated the effects of MG using tyloxapol (Tylo)-induced (200 mg/kg, i.p.) hyperlipidemia in rats and palmitic acid (PA)-stimulated (0.3 mM) HepG2 cells. Our res...

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Detalles Bibliográficos
Autores principales: Kuo, Ni-Chun, Huang, Shieh-Yang, Yang, Chien-Yi, Shen, Hsin-Hsueh, Lee, Yen-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600324/
https://www.ncbi.nlm.nih.gov/pubmed/32992548
http://dx.doi.org/10.3390/antiox9100924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600324/
https://www.ncbi.nlm.nih.gov/pubmed/32992548
http://dx.doi.org/10.3390/antiox9100924

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