Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice

Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of glucose tolerance and pancreatic transdifferentia...

Descripción completa

Detalles Bibliográficos
Autores principales: La, Que T., Ren, Binhai, Logan, Grant J., Cunningham, Sharon C., Khandekar, Neeta, Nassif, Najah T., O’Brien, Bronwyn A., Alexander, Ian E., Simpson, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600325/
https://www.ncbi.nlm.nih.gov/pubmed/33023100
http://dx.doi.org/10.3390/cells9102227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600325/
https://www.ncbi.nlm.nih.gov/pubmed/33023100
http://dx.doi.org/10.3390/cells9102227

Ejemplares similares