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Novel Approaches to Target Mutant FLT3 Leukaemia

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is a haematologic disease in which oncogenic mutations in the receptor tyrosine kinase FLT3 frequently lead to leukaemic development. Potent treatment of AML patients is still hampered by inefficient targeting of leukemic stem cells expressing constitutiv...

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Detalles Bibliográficos
Autores principales: Müller, Jörg P., Schmidt-Arras, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600363/
https://www.ncbi.nlm.nih.gov/pubmed/33003568
http://dx.doi.org/10.3390/cancers12102806