Radio-Resistance and DNA Repair in Pediatric Diffuse Midline Gliomas

SIMPLE SUMMARY: Approximately 50% of high-grade gliomas (HGG) in children are diffuse midline gliomas (DMGs), which carry the worst prognosis of all HGG, with a 2-year survival of less than 10%. DMGs are characterized by H3K27M mutation, rampant genomic instability, infiltrative growth, and radio-re...

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Detalles Bibliográficos
Autores principales: Pedersen, Henriette, Schmiegelow, Kjeld, Hamerlik, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600397/
https://www.ncbi.nlm.nih.gov/pubmed/33007840
http://dx.doi.org/10.3390/cancers12102813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600397/
https://www.ncbi.nlm.nih.gov/pubmed/33007840
http://dx.doi.org/10.3390/cancers12102813

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