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Radio-Resistance and DNA Repair in Pediatric Diffuse Midline Gliomas
SIMPLE SUMMARY: Approximately 50% of high-grade gliomas (HGG) in children are diffuse midline gliomas (DMGs), which carry the worst prognosis of all HGG, with a 2-year survival of less than 10%. DMGs are characterized by H3K27M mutation, rampant genomic instability, infiltrative growth, and radio-re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600397/ https://www.ncbi.nlm.nih.gov/pubmed/33007840 http://dx.doi.org/10.3390/cancers12102813 |