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Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation

SIMPLE SUMMARY: Loss of function of the retinoblastoma gene (RB1) is the rate-limiting step in the initiation of both the hereditary and sporadic forms of retinoblastoma tumor. Furthermore, loss of function of the retinoblastoma tumor suppressor protein (pRB) is frequently found in most human cancer...

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Detalles Bibliográficos
Autores principales: Guzman, Frederick, Fazeli, Yasamin, Khuu, Meagan, Salcido, Kelsey, Singh, Sarah, Benavente, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600434/
https://www.ncbi.nlm.nih.gov/pubmed/33003565
http://dx.doi.org/10.3390/cancers12102807