Dexamethasone Inhibits TRAIL-Induced Apoptosis through c-FLIP(L) Upregulation and DR5 Downregulation by GSK3β Activation in Cancer Cells

SIMPLE SUMMARY: Dexamethasone (DEX) is commonly used as immunosuppressive and chemotherapeutic agent. The effects of DEX on cell death is different, depending on cell types and stimuli. Here, we found that DEX inhibited tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell dea...

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Detalles Bibliográficos
Autores principales: Jeon, Mi-Yeon, Woo, Seon Min, Seo, Seung Un, Kim, Sang Hyun, Nam, Ju-Ock, Kim, Shin, Park, Jong-Wook, Kubatka, Peter, Min, Kyoung-jin, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600459/
https://www.ncbi.nlm.nih.gov/pubmed/33050333
http://dx.doi.org/10.3390/cancers12102901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600459/
https://www.ncbi.nlm.nih.gov/pubmed/33050333
http://dx.doi.org/10.3390/cancers12102901

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