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Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling

Astaxanthin (AST) is a carotenoid with therapeutic values on hyperglycemia and diabetic complications. The mechanisms of action of AST remain incompletely understood. p70 S6 kinase 1 (S6K1) is a serine/threonine kinase that phosphorylates insulin receptor substrate 1 (IRS-1)(S1101) and desensitizes...

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Detalles Bibliográficos
Autores principales: Li, Chunmei, Ma, Bixia, Chen, Junhong, Jeong, Yoonhwa, Xu, Xiulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600478/
https://www.ncbi.nlm.nih.gov/pubmed/32998286
http://dx.doi.org/10.3390/md18100495