Comparison of Effects of Metformin, Phenformin, and Inhibitors of Mitochondrial Complex I on Mitochondrial Permeability Transition and Ischemic Brain Injury

Damage to cerebral mitochondria, particularly opening of mitochondrial permeability transition pore (MPTP), is a key mechanism of ischemic brain injury, therefore, modulation of MPTP may be a potential target for a neuroprotective strategy in ischemic brain pathologies. The aim of this study was to...

Descripción completa

Detalles Bibliográficos
Autores principales: Skemiene, Kristina, Rekuviene, Evelina, Jekabsone, Aiste, Cizas, Paulius, Morkuniene, Ramune, Borutaite, Vilmante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600544/
https://www.ncbi.nlm.nih.gov/pubmed/33019635
http://dx.doi.org/10.3390/biom10101400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600544/
https://www.ncbi.nlm.nih.gov/pubmed/33019635
http://dx.doi.org/10.3390/biom10101400

Ejemplares similares