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Comparison of Effects of Metformin, Phenformin, and Inhibitors of Mitochondrial Complex I on Mitochondrial Permeability Transition and Ischemic Brain Injury

Damage to cerebral mitochondria, particularly opening of mitochondrial permeability transition pore (MPTP), is a key mechanism of ischemic brain injury, therefore, modulation of MPTP may be a potential target for a neuroprotective strategy in ischemic brain pathologies. The aim of this study was to...

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Detalles Bibliográficos
Autores principales:	Skemiene, Kristina, Rekuviene, Evelina, Jekabsone, Aiste, Cizas, Paulius, Morkuniene, Ramune, Borutaite, Vilmante
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600544/ https://www.ncbi.nlm.nih.gov/pubmed/33019635 http://dx.doi.org/10.3390/biom10101400

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