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The Impact of the CX3CL1/CX3CR1 Axis in Neurological Disorders

Fractalkine (FKN, CX3CL1) is a transmembrane chemokine expressed by neurons in the central nervous system (CNS). CX3CL1 signals through its unique receptor, CX3CR1, that is expressed in microglia. Within the CNS, fractalkine acts as a regulator of microglia activation in response to brain injury or...

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Detalles Bibliográficos
Autores principales: Pawelec, Paulina, Ziemka-Nalecz, Malgorzata, Sypecka, Joanna, Zalewska, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600611/
https://www.ncbi.nlm.nih.gov/pubmed/33065974
http://dx.doi.org/10.3390/cells9102277