JNK3 as Therapeutic Target and Biomarker in Neurodegenerative and Neurodevelopmental Brain Diseases

The c-Jun N-terminal kinase 3 (JNK3) is the JNK isoform mainly expressed in the brain. It is the most responsive to many stress stimuli in the central nervous system from ischemia to Aβ oligomers toxicity. JNK3 activity is spatial and temporal organized by its scaffold protein, in particular JIP-1 a...

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Detalles Bibliográficos
Autores principales: Musi, Clara Alice, Agrò, Graziella, Santarella, Francesco, Iervasi, Erika, Borsello, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600688/
https://www.ncbi.nlm.nih.gov/pubmed/32998477
http://dx.doi.org/10.3390/cells9102190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600688/
https://www.ncbi.nlm.nih.gov/pubmed/32998477
http://dx.doi.org/10.3390/cells9102190

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