Hp-s1 Ganglioside Suppresses Proinflammatory Responses by Inhibiting MyD88-Dependent NF-κB and JNK/p38 MAPK Pathways in Lipopolysaccharide-Stimulated Microglial Cells

Hp-s1 ganglioside is isolated from the sperm of sea urchin (Hemicentrotus pulcherrimus). In addition to neuritogenic activity, the biological function of Hp-s1 in neuroinflammation is unknown. In this study, we investigated the anti-neuroinflammatory effect of Hp-s1 on lipopolysaccharide (LPS)-stimu...

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Detalles Bibliográficos
Autores principales: Shih, Jui-Hu, Tsai, Yow-Fu, Li, I-Hsun, Chen, Ming-Hua, Huang, Yuahn-Sieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600735/
https://www.ncbi.nlm.nih.gov/pubmed/33003399
http://dx.doi.org/10.3390/md18100496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600735/
https://www.ncbi.nlm.nih.gov/pubmed/33003399
http://dx.doi.org/10.3390/md18100496

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