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Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next-Generation Sequencing Mutations Analysis across the Four World Health Organization Defined Groups

SIMPLE SUMMARY: Lung neuroendocrine neoplasms (LNENs) classes, as proposed by the World Health Organization 2015, do not provide properly prognostic and therapeutic indications. In fact, high-throughput molecular analysis, based on next-generation sequencing, identified novel molecular subgroups, as...

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Detalles Bibliográficos
Autores principales: Centonze, Giovanni, Biganzoli, Davide, Prinzi, Natalie, Pusceddu, Sara, Mangogna, Alessandro, Tamborini, Elena, Perrone, Federica, Busico, Adele, Lagano, Vincenzo, Cattaneo, Laura, Sozzi, Gabriella, Roz, Luca, Biganzoli, Elia, Milione, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600757/
https://www.ncbi.nlm.nih.gov/pubmed/32987854
http://dx.doi.org/10.3390/cancers12102753