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Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review

SIMPLE SUMMARY: Patients with advanced melanoma are often treated with v-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors. Although these agents prolong life, patients inevitably develop resistance and their cancer progresses. This review examines all of the potential ways that melanom...

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Detalles Bibliográficos
Autores principales: Proietti, Ilaria, Skroza, Nevena, Bernardini, Nicoletta, Tolino, Ersilia, Balduzzi, Veronica, Marchesiello, Anna, Michelini, Simone, Volpe, Salvatore, Mambrin, Alessandra, Mangino, Giorgio, Romeo, Giovanna, Maddalena, Patrizia, Rees, Catherine, Potenza, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600801/
https://www.ncbi.nlm.nih.gov/pubmed/33003483
http://dx.doi.org/10.3390/cancers12102801