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Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication

Influenza A virus is a major global pathogen of humans, and there is an unmet need for effective antivirals. Current antivirals against influenza A virus directly target the virus and are vulnerable to mutational resistance. Harnessing an effective host antiviral response is an attractive alternativ...

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Detalles Bibliográficos
Autores principales: Goulding, Leah V., Yang, Jiayun, Jiang, Zhimin, Zhang, Hongyu, Lea, Daniel, Emes, Richard D., Dottorini, Tania, Pu, Juan, Liu, Jinhua, Chang, Kin-Chow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600819/
https://www.ncbi.nlm.nih.gov/pubmed/32992478
http://dx.doi.org/10.3390/v12101093