Supramolecular Complexes of β-Cyclodextrin with Clomipramine and Doxepin: Effect of the Ring Substituent and Component of Drugs on Their Inclusion Topologies and Structural Flexibilities

Depression is a global threat. Tricyclic antidepressants (TCAs) are still efficacious in treating depression, albeit with more side effects. Cyclodextrins (CDs) with a suitable nanocavity are potential drug carriers and can enhance the drug bioavailability. Aiming for an atomistic understanding of t...

Descripción completa

Detalles Bibliográficos
Autor principal: Aree, Thammarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600898/
https://www.ncbi.nlm.nih.gov/pubmed/33003431
http://dx.doi.org/10.3390/ph13100278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600898/
https://www.ncbi.nlm.nih.gov/pubmed/33003431
http://dx.doi.org/10.3390/ph13100278

Ejemplares similares