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Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive tumor malignancy worldwide, mainly due to uncontrolled metastasis. Among the numerous molecules deregulated in PDAC, different members of the Akt pathways are of great importance because they are involved in tumor cell proliferation, mig...

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Detalles Bibliográficos
Autores principales: Grassilli, Silvia, Brugnoli, Federica, Lattanzio, Rossano, Buglioni, Simonetta, Bertagnolo, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600902/
https://www.ncbi.nlm.nih.gov/pubmed/32993067
http://dx.doi.org/10.3390/biomedicines8100379